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Results: 20
"YOU DEAL WITH WHAT SHE SENDS"
Nicholas Hartmann
Dec 09, 2013
ON A FREQUENT BASIS IN the province of Newfoundland and Labrador, a father, knowing that he will not be able to say goodbye to his children in the early hours of the morning, gives them a more intense goodnight hug before...
Published by: Memorial University of Newfoundland
Social Identity Theory in Sports Fandom Research
Nicholas Hirshon
May 08, 2020
Sports fans are known to engage in BIRGing, or basking in reflected glory after their team wins, and CORFing, cutting off reflected failure following a team loss. These phenomena are related to social identity theory, which...
Published by: IGI Global
Aural feedback, Vocal technique, and Creativity
Nicholas Bannan
Nov 19, 2013
This research contributes to an ongoing investigation into the instinctive nature of singing. Related projects involve: action research with children who are encouraged to reflect on the developing capacities of their own and...
Published by: Faculty of Education
Subjectivity and the Good in Plato’s Laws
Nicholas Saunders
Jul 05, 2022
n/a
Published by: Memorial University of Newfoundland
Relationship Between Physical Fitness Variables and Reaction Time in eSports Gamers
eSports gaming requires quick and accurate reactions in response to complex visual stimuli for optimal performance. The purpose of this study was to examine the relationship between components of physical fitness and reaction...
Published by: IGI Global
Foundationalism and Anti-Foundationalism in International Relations Theory
Scott Nicholas Romaniuk
Oct 07, 2014
Much has been written about the field of International Relations (IR) in both substantive and methodological terms. One of the most contentious aspects of the IR as a scholarly discipline revolves around one deceptively...
Published by: Memorial University of Newfoundland
A Context-Independent Ontological Linked Data Alignment Approach to Instance Matching
Linking data by finding matching instances in different datasets requires considering many characteristics, such as structural heterogeneity, implicit knowledge, and URI (Uniform Resource Identifier)-oriented identification. The...
Published by: IGI Global
The HAVEN study-hydroxychloroquine in ANCA vasculitis evaluation-a multicentre, randomised, double-blind, placebo-controlled trial
Annastazia E Learoyd, Lauren Arnold, Fiona Reid, Nicholas Beckley-Hoelscher, Alina Casian, Shirish Sangle, Neil Morton, Louise Nel, Angela Cape, Susan John, Sangmi Kim, Dharshene Shivapatham, Raashid Luqmani, David Jayne, James Galloway, Abdel Douiri, David D'Cruz
Apr 17, 2023
Background
Patients with non-severe ANCA-associated vasculitis (AAV) are often prescribed immunosuppressive medications that are associated with severe side effects and a reduced quality of life. There is an unmet need...
AAV Vasculitis Hydroxychloroquine Prednisolone ANCA Auto-immune conditions Humans Immunosuppressive Agents Antibodies Antineutrophil Cytoplasmic Treatment Outcome Double-Blind Method Quality of life Multicenter Studies as Topic Randomized Controlled Trials as Topic Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis covid-19 SARS-CoV-2
Published by: Trials
The HAVEN study-hydroxychloroquine in ANCA vasculitis evaluation-a multicentre, randomised, double-blind, placebo-controlled trial
Annastazia E Learoyd, Lauren Arnold, Fiona Reid, Nicholas Beckley-Hoelscher, Alina Casian, Shirish Sangle, Neil Morton, Louise Nel, Angela Cape, Susan John, Sangmi Kim, Dharshene Shivapatham, Raashid Luqmani, David Jayne, James Galloway, Abdel Douiri, David D'Cruz, HAVEN study group
Apr 06, 2023
BACKGROUND: Patients with non-severe ANCA-associated vasculitis (AAV) are often prescribed immunosuppressive medications that are associated with severe side effects and a reduced quality of life. There is an unmet need for...
Risk of Aneurysm Rupture (ROAR) study
Samuel Hall, Jacqueline Birks, Ian Anderson, Andrew Bacon, Paul M Brennan, David Bennett, Emmanuel Chavredakis, Giles Critchley, Graham Dow, Jonathan Downer, James Galea, Patrick Grover, Nihal Gurusinghe, Adel Helmy, Gueorgui Kounin, Nitin Mukerji, Hiren Patel, Jash Patel, Nicholas Ross, Jerome St George, Mario Teo, Christos Michael Tolias, Nikolaos Tzerakis, Christopher Uff, Janneke van Beijum, Kristin Veighey, Edward White, Peter Whitfield, Diederik Oliver Bulters
Apr 17, 2023
Introduction
Unruptured intracranial aneurysms (UIA) are common in the adult population, but only a relatively small proportion will rupture. It is therefore essential to have accurate estimates of rupture risk to target...
stroke EPIDEMIOLOGY Neurosurgery Humans Intracranial Aneurysm Subarachnoid Hemorrhage Aneurysm Ruptured Risk Factors Adult Multicenter Studies as Topic United Kingdom
Published by: BMJ Open
Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins.
Ganesh Agam, Christian Gebhardt, Milana Popara, Rebecca Mächtel, Julian Folz, Benjamin Ambrose, Neharika Chamachi, Sang Yoon Chung, Timothy D Craggs, Marijn de Boer, Dina Grohmann, Taekjip Ha, Andreas Hartmann, Jelle Hendrix, Verena Hirschfeld, Christian G Hübner, Thorsten Hugel, Dominik Kammerer, Hyun-Seo Kang, Achillefs N Kapanidis, Georg Krainer, Kevin Kramm, Edward A Lemke, Eitan Lerner, Emmanuel Margeat, Kirsten Martens, Jens Michaelis, Jaba Mitra, Gabriel G Moya Muñoz, Robert B Quast, Nicole C Robb, Michael Sattler, Michael Schlierf, Jonathan Schneider, Tim Schröder, Anna Sefer, Piau Siong Tan, Johann Thurn, Philip Tinnefeld, John van Noort, Shimon Weiss, Nicolas Wendler, Niels Zijlstra, Anders Barth, Claus A M Seidel, Don C Lamb, Thorben Cordes
Apr 17, 2023
Single-molecule Förster-resonance energy transfer (smFRET) experiments allow the study of biomolecular structure and dynamics in vitro and in vivo. We performed an international blind study involving 19 laboratories to assess...
Proteins Fluorescence Resonance Energy Transfer Reproducibility of Results Molecular Conformation Laboratories
Published by: Nature methods
Structural MRI predicts clinical progression in presymptomatic genetic frontotemporal dementia
Martina Bocchetta, Emily G Todd, Arabella Bouzigues, David M Cash, Jennifer M Nicholas, Rhian S Convery, Lucy L Russell, David L Thomas, Ian B Malone, Juan Eugenio Iglesias, John C van Swieten, Lize C Jiskoot, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Rik Vandenberghe, Elizabeth Finger, Fabrizio Tagliavini, Alexandre de Mendonça, Isabel Santana, Chris R Butler, Simon Ducharme, Alexander Gerhard, Adrian Danek, Johannes Levin, Markus Otto, Sandro Sorbi, Isabelle Le Ber, Florence Pasquier, Jonathan D Rohrer, Genetic Frontotemporal dementia Initiative (GENFI)
Apr 17, 2023
APOEε4 associates with microglial activation independently of Aβ plaques and tau tangles.
João Pedro Ferrari-Souza, Firoza Z Lussier, Douglas T Leffa, Joseph Therriault, Cécile Tissot, Bruna Bellaver, Pâmela CL Ferreira, Maura Malpetti, Yi-Ting Wang, Guilherme Povala, Andréa L Benedet, Nicholas J Ashton, Mira Chamoun, Stijn Servaes, Gleb Bezgin, Min Su Kang, Jenna Stevenson, Nesrine Rahmouni, Vanessa Pallen, Nina Margherita Poltronetti, John T O'Brien, James B Rowe, Ann D Cohen, Oscar L Lopez, Dana L Tudorascu, Thomas K Karikari, William E Klunk, Victor L Villemagne, Jean-Paul Soucy, Serge Gauthier, Diogo O Souza, Henrik Zetterberg, Kaj Blennow, Eduardo R Zimmer, Pedro Rosa-Neto, Tharick A Pascoal
Apr 17, 2023
Animal studies suggest that the apolipoprotein E ε4 (APOEε4) allele is a culprit of early microglial activation in Alzheimer's disease (AD). Here, we tested the association between APOEε4 status and microglial activation in...
The CAMELS Project
Abstract
The Cosmology and Astrophysics with Machine Learning Simulations (CAMELS) project was developed to combine cosmology with astrophysics through thousands of cosmological...
Francisco Villaescusa-Navarro, Shy Genel, Daniel Anglés-Alcázar, Lucia A Perez, Pablo Villanueva-Domingo, Digvijay Wadekar, Helen Shao, Faizan G Mohammad, Sultan Hassan, Emily Moser, Erwin T Lau, Luis Fernando Machado Poletti Valle, Andrina Nicola, Leander Thiele, Yongseok Jo, Oliver HE Philcox, Benjamin D Oppenheimer, Megan Tillman, ChangHoon Hahn, Neerav Kaushal, Alice Pisani, Matthew Gebhardt, Ana Maria Delgado, Joyce Caliendo, Christina Kreisch, Kaze WK Wong, William R Coulton, Michael Eickenberg, Gabriele Parimbelli, Yueying Ni, Ulrich P Steinwandel, Valentina La Torre, Romeel Dave, Nicholas Battaglia, Daisuke Nagai, David N Spergel, Lars Hernquist, Blakesley Burkhart, Desika Narayanan, Benjamin Wandelt, Rachel S Somerville, Greg L Bryan, Matteo Viel, Yin Li, Vid Irsic, Katarina Kraljic, Federico Marinacci, Mark Vogelsberger
Apr 06, 2023
p53 and ovarian carcinoma survival
Martin Köbel, Eun-Young Kang, Ashley Weir, Peter F Rambau, Cheng-Han Lee, Gregg S Nelson, Prafull Ghatage, Nicola S Meagher, Marjorie J Riggan, Jennifer Alsop, Michael S Anglesio, Matthias W Beckmann, Christiani Bisinotto, Michelle Boisen, Jessica Boros, Alison H Brand, Angela Brooks-Wilson, Michael E Carney, Penny Coulson, Madeleine Courtney-Brooks, Kara L Cushing-Haugen, Cezary Cybulski, Suha Deen, Mona A El-Bahrawy, Esther Elishaev, Ramona Erber, Sian Fereday, Anna Fischer, Simon A Gayther, Arantzazu Barquin-Garcia, Aleksandra Gentry-Maharaj, C Blake Gilks, Helena Gronwald, Marcel Grube, Paul R Harnett, Holly R Harris, Andreas D Hartkopf, Arndt Hartmann, Alexander Hein, Joy Hendley, Brenda Y Hernandez, Yajue Huang, Anna Jakubowska, Mercedes Jimenez-Linan, Michael E Jones, Catherine J Kennedy, Tomasz Kluz, Jennifer M Koziak, Jaime Lesnock, Jenny Lester, Jan Lubiński, Teri A Longacre, Maria Lycke, Constantina Mateoiu, Bryan M McCauley, Valerie McGuire, Britta Ney, Alexander Olawaiye, Sandra Orsulic, Ana Osorio, Luis Paz-Ares, Teresa Ramón Y Cajal, Joseph H Rothstein, Matthias Ruebner, Minouk J Schoemaker, Mitul Shah, Raghwa Sharma, Mark E Sherman, Yurii B Shvetsov, Naveena Singh, Helen Steed, Sarah J Storr, Aline Talhouk, Nadia Traficante, Chen Wang, Alice S Whittemore, Martin Widschwendter, Lynne R Wilkens, Stacey J Winham, Javier Benitez, Andrew Berchuck, David D Bowtell, Francisco J Candido Dos Reis, Ian Campbell, Linda S Cook, Anna DeFazio, Jennifer A Doherty, Peter A Fasching, Renée T Fortner, María J García, Marc T Goodman, Ellen L Goode, Jacek Gronwald, David G Huntsman, Beth Y Karlan, Linda E Kelemen, Stefan Kommoss, Nhu D Le, Stewart G Martin, Usha Menon, Francesmary Modugno, Paul DP Pharoah, Joellen M Schildkraut, Weiva Sieh, Annette Staebler, Karin Sundfeldt, Anthony J Swerdlow, Susan J Ramus, James D Brenton
Apr 17, 2023
p53 ovarian cancer Prognosis Clear cell TP53 High-grade Serous Carcinoma Endometrioid Humans Carcinoma Endometrioid Ovarian Neoplasms Female Tumor Suppressor Protein p53 Carcinoma Ovarian Epithelial
Published by: The journal of pathology. Clinical research
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.
Nick Shrine, Abril G Izquierdo, Jing Chen, Richard Packer, Robert J Hall, Anna L Guyatt, Chiara Batini, Rebecca J Thompson, Chandan Pavuluri, Vidhi Malik, Brian D Hobbs, Matthew Moll, Wonji Kim, Ruth Tal-Singer, Per Bakke, Katherine A Fawcett, Catherine John, Kayesha Coley, Noemi Nicole Piga, Alfred Pozarickij, Kuang Lin, Iona Y Millwood, Zhengming Chen, Liming Li, Sara R A Wijnant, Lies Lahousse, Guy Brusselle, Andre G Uitterlinden, Ani Manichaikul, Elizabeth C Oelsner, Stephen S Rich, R Graham Barr, Shona M Kerr, Veronique Vitart, Michael R Brown, Matthias Wielscher, Medea Imboden, Ayoung Jeong, Traci M Bartz, Sina A Gharib, Claudia Flexeder, Stefan Karrasch, Christian Gieger, Annette Peters, Beate Stubbe, Xiaowei Hu, Victor E Ortega, Deborah A Meyers, Eugene R Bleecker, Stacey B Gabriel, Namrata Gupta, Albert Vernon Smith, Jian'an Luan, Jing-Hua Zhao, Ailin F Hansen, Arnulf Langhammer, Cristen Willer, Laxmi Bhatta, David Porteous, Blair H Smith, Archie Campbell, Tamar Sofer, Jiwon Lee, Martha L Daviglus, Bing Yu, Elise Lim, Hanfei Xu, George T O'Connor, Gaurav Thareja, Omar M E Albagha, Karsten Suhre, Raquel Granell, Tariq O Faquih, Pieter S Hiemstra, Annelies M Slats, Benjamin H Mullin, Jennie Hui, Alan James, John Beilby, Karina Patasova, Pirro Hysi, Jukka T Koskela, Annah B Wyss, Jianping Jin, Sinjini Sikdar, Mikyeong Lee, Sebastian May-Wilson, Nicola Pirastu, Katherine A Kentistou, Peter K Joshi, Paul R H J Timmers, Alexander T Williams, Robert C Free, Xueyang Wang, John L Morrison, Frank D Gilliland, Zhanghua Chen, Carol A Wang, Rachel E Foong, Sarah E Harris, Adele Taylor, Paul Redmond, James P Cook, Anubha Mahajan, Lars Lind, Teemu Palviainen, Terho Lehtimäki, Olli T Raitakari, Jaakko Kaprio, Taina Rantanen, Kirsi H Pietiläinen, Simon R Cox, Craig E Pennell, Graham L Hall, W James Gauderman, Chris Brightling, James F Wilson, Tuula Vasankari, Tarja Laitinen, Veikko Salomaa, Dennis O Mook-Kanamori, Nicholas J Timpson, Eleftheria Zeggini, Josée Dupuis, Caroline Hayward, Ben Brumpton, Claudia Langenberg, Stefan Weiss, Georg Homuth, Carsten Oliver Schmidt, Nicole Probst-Hensch, Marjo-Riitta Jarvelin, Alanna C Morrison, Ozren Polasek, Igor Rudan, Joo-Hyeon Lee, Ian Sayers, Emma L Rawlins, Frank Dudbridge, Edwin K Silverman, David P Strachan, Robin G Walters, Andrew P Morris, Stephanie J London, Michael H Cho, Louise V Wain, Ian P Hall, Martin D Tobin
Apr 13, 2023
Lung Humans Pulmonary Disease Chronic Obstructive Genetic Predisposition to Disease Smoking Polymorphism Single Nucleotide Genome-Wide Association Study
Published by: Nature genetics